Polynucleotides and proteins encoded thereby

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/10 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 9/00 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2362422

The present invention provides novel isolated SECX polynucleotides and the membrane-associated or secreted polypeptides encoded by the SECX polynucleotides. Also provided are the antibodies that immunospecifically bind to a SECX polypeptide or any derivative, variant, mutant or fragment of the SECX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SECX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

La présente invention concerne de nouveaux polynucléotides SECX isolés ainsi que les polypeptides sécrétés ou associés aux membranes codés par ces polynucléotides SECX. En outre, cette invention concerne des anticorps qui se fixent immunospecifiquement à un polypeptide SECX ou à n'importe quel dérivé, variant, mutant ou fragment du polypeptide, polynucléotide ou anticorps SECX. De plus, cette invention concerne des procédés dans lesquels les polypeptide, polynucléotide et anticorps SECX sont utilisés, entre autres, dans la détection et le traitement d'un grand nombre d'états pathologiques.

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