A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61F 6/04 (2006.01) A61K 9/00 (2006.01) A61L 31/00 (2006.01) C12N 7/06 (2006.01)
Patent
CA 2258907
A novel formulation having anti-viral and spermacidal properties has been developed. The formulation contains lipid vesicles formed of a non-ionic amphiphile, a surfactant having spermacidal and/or anti-viral activity, an oil and a sterol. The selection of the components making the vesicle is such that the formulation provides rapid spermacidal or anti-viral activity. The formulation and methods of the invention are particularly useful in the mucous membranes such as the vaginal tract and has been tested against viruses such as HIV and Vaccinia.
Une nouvelle formulation ayant des propriétés antivirales et spermicides a été mise au point. Cette formulation contient des vésicules lipidiques formées d'un amphiphile non ionique, d'un tensioactif à activité spermicide et/ou antivirale, d'une huile et d'un stérol. Le choix des constituants de la vésicule est tel que la formulation possède une activité spermicide ou antivirale rapide. Cette formulation et les procédés décrits sont particulièrement utiles dans les membranes muqueuses telles que le tractus vaginal. L'efficacité de cette formulation a été testée contre des virus tels que le VIH et la vaccine.
Wright D. Craig
Novavax Inc.
Riches Mckenzie & Herbert Llp
LandOfFree
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