Virulence genes, proteins, and their use

Details Virulence genes, proteins, and their use Virulence genes, proteins, and their use

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 38/00 (2006.01) A61K 39/095 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 1/36 (2006.01) C12Q 1/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2408738

A series of genes from Neisseria meningitidis are shown to encode products which are implicated in virulence. The identification of these genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used in the manufacture of vaccines for therapeutic application.

L'invention concerne une série de gènes Neisseria meningitidis, qui codent des produits impliqués dans la virulence. L'identification de ces gènes permet donc la production de micro-organismes atténués. En outre, ces gènes ou leurs produits codés peuvent être utilisés dans la préparation de vaccins pour des applications thérapeutiques.

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