Methods of identifying potential components for targeted...

Details Methods of identifying potential components for targeted... Methods of identifying potential components for targeted...

A - Human Necessities

61

K

A61K 47/34 (2006.01)

Patent

CA 2756924

Methods of preparing compositions for preferential distribution of active agents to injury sites are provided. The compositions may comprise a polymer with hydrophilic properties and one or more active agents, such as compounds comprising hydrophilic metal ions. Because the delivery ligand and the active agent are specifically selected so the interactions between them are mainly of an ionic nature. Methods of identifying suitable components for such compositions are also disclosed.

L'invention propose des procédés de préparation de compositions pour la distribution préférentielle d'agents actifs en des sites lésés. Les compositions peuvent comprendre un polymère ayant des propriétés hydrophiles et un ou plusieurs agents actifs, comme des composés comprenant des ions métalliques hydrophiles. Le ligand de délivrance et l'agent actif sont spécifiquement choisis pour que les interactions entre eux soient principalement de nature ionique. L'invention propose également, des procédés d'identification de composants appropriés pour de telles compositions.

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