Heterocyclic amide derivatives as ep4 receptor antagonists

Details Heterocyclic amide derivatives as ep4 receptor antagonists Heterocyclic amide derivatives as ep4 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/407 (2006.01) A61K 31/423 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61K 31/535 (2006.01) C07D 209/34 (2006.01) C07D 263/54 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2733247

The invention relates to compounds of Formula (I) (or pharmaceutically acceptable salts thereof) as defined herein, pharmaceutical compositions thereof, and their use in manufactures and methods for modulating biological processes including antagonism of Prostaglandin EP4 receptor as a therapeutic treatment.

Linvention concerne des composés de formule (I) (ou leurs sels pharmaceutiquement acceptables) telle que définie dans ce document, leurs compositions pharmaceutiques et leur utilisation dans des fabrications et des procédés de modulation de processus biologiques y compris lantagonisme du récepteur EP4 des prostaglandines en tant que traitement thérapeutique.

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