Method of enhancing mucosal hydration and mucosal clearance...

Details Method of enhancing mucosal hydration and mucosal clearance... Method of enhancing mucosal hydration and mucosal clearance...

A - Human Necessities

61

K

A61K 31/4965 (2006.01) A61K 9/12 (2006.01) A61K 31/047 (2006.01) A61K 33/14 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2663041

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

La présente invention concerne des procédés et compositions pour traiter des maladies, améliorés par une clairance mucociliaire et une hydratation de muqueuse augmentées en administrant à un sujet ayant besoin d'une clairance mucociliaire et d'une hydratation de muqueuse améliorées une quantité efficace d'un bloqueur de canal sodique tel que défini ici et un osmolyte.

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