Quinoline derivatives and quinazoline derivatives,...

Details Quinoline derivatives and quinazoline derivatives,... Quinoline derivatives and quinazoline derivatives,...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4706 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 239/94 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2540501

The invention relates to bicyclic heterocycles of general formula (I), wherein Ra, Rb, Rc, Rd, and X are defined as indicated in claim 1, the tautomers, stereoisomers, mixtures, and salts thereof, especially the physiologically acceptable salts thereof with inorganic or organic acids that have valuable pharmacological properties, particularly an inhibitory effect on the signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, above all tumor diseases, benign prostate hyperplasia (BPH), and diseases of the lung and respiratory tract, and the production thereof.

L'invention concerne des hétérocycles bicycliques de formule générale (I), dans laquelle R?a¿, R?b¿, R?c¿, R?d¿ et X sont tels que définis dans la revendication n· 1, ainsi que les tautomères, stéréo-isomères, mélanges et sels de ces composés, en particulier les sels physiologiquement tolérables de ces composés avec des acides inorganiques ou organiques. Lesdits composés présentent des propriétés pharmacologiques intéressantes, notamment une action inhibitrice sur la transduction de signaux à médiation par les tyrosine kinases. L'invention concerne également l'utilisation de ces composés pour traiter des maladies, en particulier des maladies tumorales et l'hyperplasie bénigne de la prostate (BPH), des maladies des poumons et des voies respiratoires, ainsi que la production desdits composés.

Affiliated with

Also associated with

Rating

Quinoline derivatives and quinazoline derivatives,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Quinoline derivatives and quinazoline derivatives,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinoline derivatives and quinazoline derivatives,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1714269