Intermittent dosing regimen for overweight and obese subjects

A - Human Necessities – 61 – K

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A61K 31/496 (2006.01)

Patent

CA 2562015

The present invention concerns an intermittent dosing regimen for the treatment of obesity or the reduction of body weight wherein a pharmaceutical composition containing an apoB secretion/MTP inhibitor is administered to a subject in need thereof for a period of time, then withheld for a period of time, and again administered for a period of time. The intermittent regimen may be repeated depending on the response in the subject that is being sought.

L'invention concerne un schéma posologique de dosage intermittent destiné au traitement de l'obésité ou à la perte de poids corporel. Une composition pharmaceutique contenant un inhibiteur apoB secretion/MTP est administrée à un sujet souffrant de ces pathologies sur une période prédéterminée, puis retenue sur une période prédéterminée, et enfin elle est administrée de nouveau pendant une période prédéterminée. Le schéma posologique intermittent peut être répété en fonction de la réponse du sujet.

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