Antibiotics containing borinic acid complexes and methods of...

C - Chemistry – Metallurgy – 07 – F

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C07F 5/02 (2006.01) A61K 31/69 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2509645

The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.

L'invention concerne la structure et la préparation d'antibiotiques comprenant des complexes d'acide borinique, notamment des dérivés d'acide picolinique, d'imidazole, et d'hydroquinoléine. L'invention porte également sur des compositions desdits antibiotiques ainsi que sur des procédés d'utilisation desdits antibiotiques et compositions en tant qu'agents bactéricides et fongicides et en tant qu'agents thérapeutiques pour le traitement de maladies induites par des bactéries et des champignons.

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