Substituted piperazine compounds and their use as fatty acid...

Details Substituted piperazine compounds and their use as fatty acid... Substituted piperazine compounds and their use as fatty acid...

C - Chemistry, Metallurgy

07

D

C07D 277/64 (2006.01) A61K 31/496 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2579621

Disclosed are novel piperazine and piperazine derivatives of formula (I), useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, diabetes, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction.

L'invention concerne de nouveaux dérivés de piperazine et de piperazine utiles pour le traitement de divers états pathologiques, notamment des maladies cardiovasculaires telles que les arythmies atriales et ventriculaires, le diabète, la claudication intermittente, l'angine de poitrine inversée, l'angine stable et instable, l'angine provoquée par l'effort, l'insuffisance cardiaque globale et l'infarctus du myocarde.

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