Procaspase 8-mediated disease targeting

A - Human Necessities – 61 – K

Patent

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Details

A61K 49/00 (2006.01) A61K 9/16 (2006.01) A61K 31/337 (2006.01) A61K 39/395 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61K 49/04 (2006.01) A61K 49/14 (2006.01) A61K 49/22 (2006.01) A61K 51/08 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2679643

The invention provides compositions and method for delivering a therapeutic or diagnostic agent to a disease site in a mammal, the method comprising administering to the mammal a therapeutically or diagnostically effective amount of a pharmaceutical composition, wherein the pharmaceutical composition comprises the therapeutic or diagnostic agent coupled to a Procaspase 8 polypeptide and a pharmaceutically acceptable carrier.

La présente invention concerne des compositions et un procédé destinés à administrer un agent thérapeutique ou diagnostique sur un site malade d'un mammifère, le procédé comprenant l'administration au mammifère d'une quantité efficace d'un point de vue thérapeutique ou diagnostique d'une composition pharmaceutique comprenant l'agent thérapeutique ou diagnostique couplé à un polypeptide pro-caspase-8 et à un vecteur acceptable d'un point de vue pharmaceutique.

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