Bipotential liver cell lines from wild-type mammalian liver...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/071 (2010.01) C12N 5/074 (2010.01) A01K 67/00 (2006.01) A61K 35/407 (2006.01) A61K 35/413 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2444292

The present invention relates to a hepatic cell line derived from wild-type mammalian liver tissue by culture methodology, the cells of the cell line being capable of differentiating into hepatocytes and bile duct cells. The present invention also relates to methods of producing such cells as well as to their applications in therapy and as an investigational tool.

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