New n-aryl and n-heteroarylurea derivatives as inhibitors of...

Details New n-aryl and n-heteroarylurea derivatives as inhibitors of... New n-aryl and n-heteroarylurea derivatives as inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 213/75 (2006.01) A61K 31/17 (2006.01) A61K 31/38 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) C07C 275/28 (2006.01) C07D 215/38 (2006.01) C07D 217/22 (2006.01) C07D 239/58 (2006.01) C07D 307/82 (2006.01) C07D 333/58 (2006.01) C07D 333/66 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2134359

A compound of formula (I), the pharmaceutically acceptable salts thereof, wherein Q, R17, R18 and R1 are as defined below. The compounds of formula (I) are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.

Composé de formule (I) et leurs sels acceptables en pharmacie, où Q, R17, R18 et R1 correspondent aux définitions données ci-dessous. Les composés de formule (I) sont des inhibiteurs de l'acyl-coenzyme-A-cholestérol-acyltransférase (ACAT) et sont utiles comme agents hypolipidémiques et anti-athérosclérose.

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