Method of determining xenograft responses

Details Method of determining xenograft responses Method of determining xenograft responses

G - Physics

01

N

G01N 33/48 (2006.01)

Patent

CA 2521614

The present invention provides a method of modifying or engineering cells that are intended for introduction into a host as a xenograft, the modification or engineering of the cells comprising inclusion of at least one suitable reporter system. Inclusion of a reporter system permits monitoring of the xenograft and determination of xenograft parameters of interest through appropriate and convenient measurement systems.

La présente invention a trait à un procédé de modification ou de transformation génétique de cellules destinées à être introduites chez un hôte sous forme de xénogreffe, la modification ou la transformation génétique des cellules comprenant l'inclusion d'au moins un système de rapporteur approprié. L'inclusion d'un système de rapporteur permet le suivi de la xénogreffe et la détermination de paramètres de xénogreffe d'intérêt par des systèmes de mesure appropriés et simples.

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