Method of treating men with testosterone supplement and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/58 (2006.01) A61P 15/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2602386

A method of treating Alzheimer~s disease, Parkinson~s disease, sexual dysfunction or erectile dysfunction in a man by administration of a 5alpha reductase inhibitor together with a testosterone supplement is described. The method is also concerned with the use of the 5alpha reductase inhibiting compound and the testosterone supplement together with another agent useful for treating erectile dysfunction, including PDE V inhibitors; AGE (advanced glycation end-product) breakers; alpha 1 blockers; alpha 1A antagonists; alpha 2 antagonists; dopamine agonists; dopamine D4 agonists; melanocortin agonists; oxytocin agonists; prostaglandin; radical scavengers; rotamase inhibitors; aviptadil; nitroglycerine; and GPCR agonists for treating male sexual dysfunction or erectile dysfunction.

La présente invention concerne un traitement de la maladie d'Alzheimer, de la maladie de Parkinson, de dysfonctions sexuelles ou du trouble de l'érection par administration d'un inhibiteur de la 5.alpha.-réductase asociée à un supplément de testérone. L'invention concerne également, pour traiter les dysfonctions sexuelles et le trouble de l'érection, l'utilisation du composé inhibiteur de la 5.alpha.-réductase associé à un autre principe convenant au traitement du trouble de l'érection, et notamment les inhibiteurs de la PDE V (PhosphoDiEstérase de type V), les interrupteurs AGE (Advanced Glycation End-product), les .alpha.-1-bloquants, les antagonistes .alpha.-1A, les antgonistes .alpha.-2, les agonistes dopaminiques, les agonistes dopaminiques DA, les agonistes mélanocortiniques, les agonistes oxytociniques, la prostaglandine, les capteurs de radicaux, les inhibiteurs des rotamases, l'aviptadil, la nitroglycérine, et les agonistes des RCPG (Récepteurs Couplés aux Protéines G).

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