Creams containing vitamin d3 derivatives

Details Creams containing vitamin d3 derivatives Creams containing vitamin d3 derivatives

A - Human Necessities

61

K

A61K 31/59 (2006.01) A61K 9/06 (2006.01) A61K 47/00 (2006.01) A61K 47/30 (2006.01) A61K 47/06 (2006.01) A61K 47/10 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2312731

O/W type creams wherein the percutaneous absorbability and heat stability of maxacalcitol, i.e., the active ingredient, have been improved. Namely, O/W type creams containing maxacalcitol in the oily phase and/or the aqueous phase. More particularly speaking, O/W type creams containing maxacalcitol and emulsifiers characterized in that maxacalcitol is contained in the oily phase, and ones characterized in that maxacalcitol is contained in the aqueous phase.

La présente invention concerne des émulsions aqueuses dans lesquelles on a amélioré l'absorbabilité percutanée et la stabilité thermique du maxacalcitol qui y est le principe actif. En l'occurrence, l'invention concerne des émulsions aqueuses où le maxacalcitol se trouve aussi bien dans la phase huileuse que dans la phase aqueuse. L'invention concerne plus particulièrement des émulsions aqueuses à base de maxacalcitol et d'émulsifiant, et caractérisées, pour les unes en ce que le maxacalcitol se trouve dans la phase huileuse, et pour les autres en ce que le maxacalcitol se trouve dans la phase aqueuse.

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