A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2440831
The invention provides for the treatment of diseases or disorders characterized by cells expressing the CD40 membrane glycoprotein. The invention provides methods for the treatment of various diseases or disorders characterized by cells expressing CD40 with a combination of an agent causes the depletion of cells expressing CD40 and a second agent which causes the depletion of cells expressing the CD20 membrane antigen. Pharmaceutical compositions and articles of manufacture such as kits comprising the agents and combinations thereof are also provided.
L'invention concerne le traitement de maladies ou d'affections caractérisées par des cellules exprimant la glycoprotéine membranaire CD40. L'invention concerne notamment des méthodes de traitement de diverses maladies ou affections caractérisées par des cellules exprimant l'antigène CD40 au moyen d'un agent provoquant la déplétion des cellules exprimant l'antigène CD40 combiné à un second agent provoquant la déplétion des cellules exprimant l'antigène membranaire CD20. L'invention concerne également des compositions pharmaceutiques et des articles de fabrication, tels que des nécessaires, comprenant ces agents et des combinaisons de ceux-ci.
Genentech Inc.
Smart & Biggar
LandOfFree
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