Cell growth and cell transplant devices for gene therapy

Details Cell growth and cell transplant devices for gene therapy Cell growth and cell transplant devices for gene therapy

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01)

Patent

CA 2613640

An artificial tendon, ligament, bone and skin panel are provided, made of biocompatible materials and capable of being seeded and eventually coated with selected cell types. Seeded or coated artificial tendon, ligament, bone or skin panels can be shaped and implanted in mammals. Implantable cell growth cages may be seeded with selected cell types and used to produce desired gene expression products within a mammal. Gene expression products may be harvested from transfected animal cells cultured in a cell growth chamber.

L'invention porte sur un tendon, un ligament, un os et un pan de peau artificiels fabriqués dans des matériaux biocompatibles et pouvant être ensemencés et finalement recouverts de types de cellules choisis. Les tendons, ligaments, os ou pans de peau artificiels ensemencés ou recouverts peuvent être mis en forme et implantés chez des mammifères. Des cages de croissance cellulaire peuvent être ensemencées avec des types de cellules connus et utilisées pour produire des produits d'expression génique désirés chez un mammifère. Les produits d'expression génique peuvent être récoltés de cellules animales transfectées mises en culture dans une chambre de croissance cellulaire.

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