Process for monitoring and detecting small molecule -...

Details Process for monitoring and detecting small molecule -... Process for monitoring and detecting small molecule -...

G - Physics

01

N

G01N 29/00 (2006.01) G01N 27/00 (2006.01) G01N 29/02 (2006.01) G01N 33/15 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2271179

Small molecules (molecular weight less than about 2800) are screened for interaction with biomolecules by contacting a solution containing the small molecule with immobilized biomolecules under test, and generating acoustic waves in the solution using an acoustic wave device. Interaction of the small molecules with the immobilized biomolecules causes a change in frequency of the acoustic waves, which can be detected and analyzed electronically to monitor the interaction.

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