Spiro derivatives and adhesion molecule inhibitors...

Details Spiro derivatives and adhesion molecule inhibitors... Spiro derivatives and adhesion molecule inhibitors...

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61K 31/4545 (2006.01) A61K 31/499 (2006.01) A61K 31/55 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 11/06 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) A61P 19/02 (2006.01) A61P 27/14 (2006.01) A61P 27/16 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2423007

Disclosed are novel spiro derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases. The spiro derivative according to the present invention has the chemical structure, for example, represented by the following Formula (31): Image

L'invention concerne de nouveaux composés spiro et leur utilisation comme médicaments, en particulier des inhibiteurs de molécules d'adhésion utiles dans le traitement de maladies inflammatoires. Un exemple de ces composés spiro a une structure chimique représentée par la formule générale (31).

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