Heterobicyclic thiophene compounds and methods of use

Details Heterobicyclic thiophene compounds and methods of use Heterobicyclic thiophene compounds and methods of use

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4353 (2006.01) A61K 31/439 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2636242

Compounds of Formula I and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula I and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

L'invention porte sur des composés de formule (I) et leurs sels pharmaceutiquement acceptables inhibant le récepteur des tyrosine kinases et traitant des troubles médiés par elles, et sur des méthodes les utilisant permettant d'effectuer des diagnostics in vitro, in situ et in vivo, et de prévenir ou traiter de tels troubles dans des cellules mammifères ou les états pathologiques associées.

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