Zosuquidar, daunorubicin, and cytarabine for the treatment...

Details Zosuquidar, daunorubicin, and cytarabine for the treatment... Zosuquidar, daunorubicin, and cytarabine for the treatment...

A - Human Necessities

61

K

A61K 31/497 (2006.01)

Patent

CA 2614324

The present invention relates to a method of treating patients with solid tumors, leukemias, and other malignancies using a combination of zosuquidar, daunorubicin, and cytarabine. The invention is also directed to pharmaceutical formulations comprising zosuquidar, daunorubicin, and cytarabine. The formulations are particularly effective in treating newly diagnosed Acute Myelogenous Leukemia (AML).

La présente invention concerne une méthode destinée à traiter des patients présentant des tumeurs solides, des leucémies et d'autres tumeurs malignes au moyen d'une combinaison de zosuquidar, de daunorubicine et de cytarabine. L'invention concerne également des préparations pharmaceutiques comprenant du zosuquidar, de la daunorubicine et de la cytarabine. Ces préparations sont particulièrement efficaces dans le traitement d'une leucémie myélogène aiguë (LMA) nouvellement diagnostiquée.

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