Mutants of the factor vii epidermal growth factor domain

Details Mutants of the factor vii epidermal growth factor domain Mutants of the factor vii epidermal growth factor domain

C - Chemistry, Metallurgy

12

N

C12N 9/94 (2006.01)

Patent

CA 2528239

The application relates to modified blood coagulation factor, sequencing encoding such modified factors, processes for their production, and related pharmaceutical compositions comprising such factors and their uses. More specifically, the application relates to mutations in the human FVII EGF-1 domain, wherein said mutations were analyzed for clotting activity, amidolytic activity and affinity of binding to full-length, relipidated human TF by competitive ELISA.

La présente invention se rapporte à un facteur de coagulation sanguine modifié, au séquençage et codage de ces facteurs modifiés, à des procédés de production de ces derniers, à des compositions pharmaceutiques connexes comprenant les facteurs précités et à l'utilisation desdites compositions. En particulier, l'invention concerne des mutations dans le domaine du FVII EGF-1 humain, lesdites mutations ayant été soumises à une analyse par test ELISA compétitif à la recherche d'une activité de coagulation, d'une activité amidolytique et d'une affinité de liaison avec un facteur tissulaire (TF) humain relipidé de pleine longueur.

Affiliated with

Also associated with

Rating

Mutants of the factor vii epidermal growth factor domain does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mutants of the factor vii epidermal growth factor domain, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mutants of the factor vii epidermal growth factor domain will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1718313