A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/02 (2006.01) C12N 9/64 (2006.01) C12N 15/00 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2306983
A method of treatment for human patients with an acquired hypercoagulable state or acquired protein C deficiency associated with sepsis, purpura fulminans, meningococcal sepsis, bone marrow and other transplantations, severe burns, pregnancy, major surgery, severe trauma, or ARDS, which comprises administering activated protein C providing a highly selective therapeutic agent with a low potential for causing bleeding complications.
L'invention concerne une méthode de traitement de patients humains présentant un état d'hypercoagulabilité acquis ou une carence acquise en protéine C associée à une septicémie, un purpura fulminans, une septicémie méningococcique, une transplantation de moelle osseuse ou d'autres transplantations, des brûlures graves, une grossesse, une intervention chirurgicale importante, un trauma grave, ou une insuffisance respiratoire aiguë des états de choc; la méthode de traitement consiste à administrer une protéine C activée constituant un agent thérapeutique hautement sélectif peu susceptible de provoquer des complications hémorragiques.
Grinnell Brian William
Hartman Daniel Lawrence
Yan Sau-Chi Betty
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
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