C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2220849
68772 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing 68772 polypeptides and polynucleotides in the design of protocols for the treatment of proliferative diseases such as leukemias, solid tumor cancers and metastases; chronic inflammatory proliferative diseases such as psoriasis and rheumatoid arthritis; proliferative cardiovascular diseases such as restenosis; prolifertive ocular disorders such as diabetic retinopathy; and benign hyperproliferative diseases such as hemangiomas, among others, and diagnostic assays for such conditions.
Divulgation de polypeptides et de polynucléotides, 68772 ainsi que de méthodes de production de tels polypeptides par des techniques de recombinaison. Des méthodes pour utiliser les polypeptides et les polynucléotides 68772 dans la conception de protocoles pour le traitement de maladies prolifératives comme les leucémies, les tumeurs cancéreuses solides et les métastases; les maladies prolifératives inflammatoires chroniques comme le psoriasis et la polyarthrite rhumatoïde; les maladies cardio-vasculaires prolifératives comme la resténose; les troubles oculaires prolifératifs comme la rétinopathie diabétique; et les maladies hyperprolifératives bénignes comme les hémangiomes, entre autres, ainsi que des méthodes diagnostiques pour ces conditions sont également dévoilées.
Hansbury Michael Joseph
Jackson Jeffrey Richard
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