Tetrahydropyridine derivative having substituents on three...

Details Tetrahydropyridine derivative having substituents on three... Tetrahydropyridine derivative having substituents on three...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2133750

A tetrahydropyridine derivative having substituents on three rings represented by the following formula (1): (See formula I) (wherein A represents sulfur. atom, sulfoxide group or sulfone group; R1 represents an amino group substituted with a specific substituent or a specific aliphatic oxy group; R2 and R3 each represents hydrogen atom or a hydroxy group; and m and n are each an integer of from 0 to 4; provided that when m and n are 2 or above, R2's and R3's may be either the same or different from each other respectively, that when A is sulfur atom and R1 is cyclohexylamino group and R2 is hydrogen atom, R3 is hydroxy group, that when A is sulfoxide group and R1 is cyclohexylamino group or 4-hydroxycyclohexyl- amino group, R2 is hydrogen atom and R3 is hydrogen atom or hydroxy group and that when A is sulfone group and R1 is cyclohexylamino group, R2 and R3 are each hydrogen atom) and an acid addition salt thereof is to be provided, thereby a compound which is useful as a psychotropic drug having anxiolytic and learning-improvement effects is to be provided.

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