Inhibition of emmprin to treat multiple sclerosis

Details Inhibition of emmprin to treat multiple sclerosis Inhibition of emmprin to treat multiple sclerosis

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/713 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2725534

The present invention provides new methods for the prevention of migration of leukocytes into the CNS. These methods, which rely on inhibition of EMMPRIN activity or expression, can be used to treat or slow the onset of diseases such as multiple sclerosis and EAE.

La présente invention concerne de nouveaux procédés pour la prévention de la migration des leucocytes dans le SNC. Ces procédés, qui reposent sur l'inhibition de l'activité ou de l'expression d'EMMPRIN, peuvent être utilisés pour traiter ou ralentir le déclenchement de maladies comme la sclérose en plaques et l'EAE.

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