Use of a c1 esterase inhibitor for preventing or delaying...

A - Human Necessities – 61 – K

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A61K 38/46 (2006.01) A61K 38/57 (2006.01)

Patent

CA 2376716

The use of a preparation comprising a C1 esterase inhibitor (C1-INH) for preventing or delaying hyperacute and/or acute rejection of xenotransplants in mammals is described. The xenotransplantation is preferably carried out in such a way that a therapeutically effective amount of the C1-INH preparation is administered to the recipient organism before the transplantation and, after the transplant- ation has taken place, the organism receives daily doses of the C1-INH preparation in an amount sufficient to prevent rejection of the transplant.

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