Tricyclic compounds useful for inhibition of farnesyl...

Details Tricyclic compounds useful for inhibition of farnesyl... Tricyclic compounds useful for inhibition of farnesyl...

C - Chemistry, Metallurgy

07

D

C07D 221/16 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 211/32 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2217477

Novel compounds of Formula (1.0) are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of Formula (1.0) to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

Composés nouveaux de formule (1.0). Est également décrit un procédé d'inhibition de la fonction Ras, et donc d'inhibition de la croissance anormale des cellules. Le procédé consiste à administrer un composé de la formule indiquée à un système biologique. Le procédé inhibe en particulier la croissance anormale des cellules chez les mammifères tels que l'homme.

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