West nile virus antigent and assay

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/40 (2006.01) C07K 14/08 (2006.01) C07K 14/18 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2554500

The present invention provides for a polypeptide comprising a fragment of the West Nile Virus E protein, wherein the E protein fragment consists of residues 1-428. The invention also provides for polynucleotides encoding this protein and host cells transformed genetically to express this protein. More particularly, the invention provides for assays and diagnostic kits for the detection of West Nile Virus E protein antibody that circulates in the blood of patients thought to be afflicted with West Nile disease.

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