Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and...

Details Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and... Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2259222

The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula (I) to said mammal.

Cette invention se rapporte à des composés représentés par la formule (I) où R¿1?, R¿2?, R¿3? et R¿4? sont définis dans les pièces descriptives de la demande de brevet. Cette invention se rapporte également à des compositions pharmaceutiques contenant ces composés de formule (I) et à des procédés pour inhiber chez un mammifère une croissance cellulaire anormale, comme dans le cas du cancer, en lui administrant des composés de cette formule (I).

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