Use of atazanavir for improving the pharmacokinetics of...

Details Use of atazanavir for improving the pharmacokinetics of... Use of atazanavir for improving the pharmacokinetics of...

A - Human Necessities

61

K

A61K 31/513 (2006.01) A61K 31/4418 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2588466

A method for improving the pharmacokinetics of an orally administered drug that is directly metabolized by UGT1A1 comprises orally administering to a mammal in need of treatment with the drug a combination of the drug or a pharmaceutically acceptable salt thereof and atazanavir or a pharmaceutically acceptable salt thereof.

L'invention concerne un procédé destiné à améliorer les propriétés pharmacocinétiques d'un médicament à administration orale, métabolisé directement par UGT1A1. Ledit procédé consiste à administrer par voie orale, à un mammifère nécessitant un traitement par ce médicament, une combinaison dudit médicament ou d'un sel pharmaceutiquement acceptable dudit médicament et d'atazanavir ou d'un sel pharmaceutiquement acceptable d'atazanavir.

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