Methods and compositions for mitochondrial replacement therapy

Details Methods and compositions for mitochondrial replacement therapy Methods and compositions for mitochondrial replacement therapy

A - Human Necessities

61

K

A61K 35/12 (2006.01) A61P 9/10 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) A61P 27/02 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2688125

The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities.

L'invention concerne des procédés, des trousses et des compositions destinés à assurer le remplacement des mitochondries dans le cadre du traitement d'affections dues à un dysfonctionnement des mitochondries. L'invention concerne également des procédés de diagnostic d'affections neuropsychiatriques (par exemple les troubles bipolaires) et neurodégénératives sur la base d'anomalies structurelles affectant les mitochondries.

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