Quinoline derivatives as neuropeptide y antagonists

Details Quinoline derivatives as neuropeptide y antagonists Quinoline derivatives as neuropeptide y antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/4709 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2460865

Compounds of formula (I), as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.

L'invention concerne des composés correspondant à la formule (I), ainsi que des sels et des esters pharmaceutiquement acceptables de ceux-ci. Dans ladite formule (I), R?1¿, R?2¿, R?3¿, A?1¿ et A?2¿ correspondent à la définition donnée dans la revendication 1. Ces composés, leurs sels et esters pharmaceutiquement acceptables peuvent être utilisés sous la forme de préparations pharmaceutiques pour le traitement ou la prévention de l'arthrite, de maladies cardio-vasculaires, du diabète, de l'insuffisance rénale, des troubles de l'alimentation et de l'obésité.

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