Use of ketamine for facilitating detoxification and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/135 (2006.01) A61K 9/12 (2006.01) A61K 9/68 (2006.01) A61K 9/72 (2006.01) A61M 11/00 (2006.01) A61K 31/551 (2006.01)

Patent

CA 2213567

The present invention relates to facilitating detoxification and treatment of substance addiction. Accordingly, the present invention is broadly directed to a method for treating substance addiction subject comprising administering ketamine in an amount effective to facilitate detoxification or assist in overcoming substance addiction, or both. The present invention is broadly directed to transmucosal administration of ketamine. In a further embodiment, the present invention provides for parenteral administration of ketamine. Treatment with ketamine advantageously allows for patient self administration of the drug, which provides for management or treatment of a substance addiction on an outpatient basis. Moreover, ketamine administration in nasal sprays and inhalers are generally socially acceptable. In a specific example, a dedicated smoker was able to reduce her craving from three packs of ciga rettes a day.

La présente invention concerne un procédé pour faciliter la désintoxication et le traitement de l'accoutumance à une substance. Par conséquent, l'invention concerne un procédé pour traiter un sujet accoutumé à une substance . Ce procédé consiste à administrer à ce sujet de la kétamine selon une quantité efficace pour faciliter la désintoxication ou l'aider à vaincre son accoutumance à la substance. L'invention a pour objet l'administration de kétamine en assurant son absorption par les muqueuses. Dans un autre mode de réalisation, la présente invention prévoit l'administration parentérale de kétamine. Le traitement par kétamine permet de manière avantageuse l'auto-administration du produit par le patient, ce qui permet de traiter l'accoutumance à une substance en ambulatoire. En outre, l'administration de kétamine par pulvérisations nasales ou inhalateurs est généralement acceptable d'un point de vue social. Dans un exemple spécifique, une femme fumant trois paquets de cigarettes par jour a pu diminuer sa consommation.

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