Methods and compositions for targeted single-stranded...

Details Methods and compositions for targeted single-stranded... Methods and compositions for targeted single-stranded...

C - Chemistry, Metallurgy

12

N

C12N 9/22 (2006.01) C07K 19/00 (2006.01) C12N 15/09 (2006.01) C12N 15/62 (2006.01) C12N 15/90 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2734235

Disclosed herein are methods and compositions for generating a single-stranded break in a target sequence, which facilitates targeted integration of one or more exogenous sequences.

L'invention porte sur des procédés et des compositions de génération d'une rupture simple brin dans une séquence cible, ce qui facilite une intégration ciblée d'une ou plusieurs séquences exogènes.

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