Transdermal transport using ultrasonic standing waves

Details Transdermal transport using ultrasonic standing waves Transdermal transport using ultrasonic standing waves

A - Human Necessities

61

B

A61B 5/00 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2245712

A process for the sampling of extracellular fluid across the skin of an animal involves establishing an ultrasonic standing wave across the skin and collecting fluid transudate. Sampling can be enhanced by combining the use of ultrasound with the application of a partial vacuum to the surface of the skin. An apparatus includes an ultrasonic transducer, a reflector and an absorbent material for collecting transudate. The apparatus can further include a pressure component for reducing hydrostatic pressure on the skin surface.

La présente invention concerne un procédé de prélèvement de liquide extracellulaire au travers de la peau d'un animal. Ce procédé nécessite l'établissement d'une onde ultrasonore stationnaire traversant la peau et la récupération du transsudat du liquide. On peut obtenir un meilleur prélèvement en associant à l'ultrason l'application d'un vide partiel à la surface de la peau. L'invention concerne également un appareil comprenant un transducteur d'ultrasons, un réflecteur et un matériau absorbant permettant la récupération du transsudat. L'appareil peut également comprendre un module à dépression permettant de réduire la pression hydrostatique sur la surface de la peau.

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