Spiro-substituted tetrahydroquinazolines as corticotropin...

A - Human Necessities – 61 – K

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A61K 31/517 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 239/70 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2535249

Compounds of the formula (I): and pharmaceutically acceptable salts or prodrugs thereof, wherein m, n, R1,R2 R3, R4, R5, R6, R7, R8, and R9 are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula (I) for the preparation of medicaments containing them.

L'invention concerne des composés de formule (I), ainsi que des sels pharmaceutiquement acceptables ou des promédicaments de ces composés. Dans ladite formule (I) : m, n, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿ et R?9¿ sont tels que définis dans la description. La présente invention concerne également des procédés pour préparer les composés de formule (I), des compositions les contenant, ainsi que des procédés d'utilisation desdits composés pour préparer des médicaments les contenant.

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