Non-simian cells for growth of porcine reproductive and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/073 (2010.01) C12N 5/071 (2010.01) A61K 39/12 (2006.01) C12N 5/02 (2006.01) C12N 7/00 (2006.01) C12N 7/08 (2006.01)

Patent

CA 2675139

Disclosed are compositions and methods relating to growth of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) using non-simian cells. In a particular example, porcine alveolar macrophage cells are described as having a capability of supporting infectivity and reproduction by PRRSV. Cells and cell lines of the invention are disclosed in connection with applications relating to PRRS disease, including vaccine technologies.

Cette invention concerne des compositions et des méthodes associées au développement du virus du syndrome dysgénésique et respiratoire du porc (virus PRRS) au moyen de cellules non simiennes. Un exemple particulier décrit dans cette invention concerne des macrophages alvéolaires porcins qui présentent la capacité d'encourager l'infectiosité et la reproduction par le virus PRRS. Les cellules et les lignées cellulaires décrites dans cette invention peuvent être utilisées dans des applications associées au syndrome dysgénésique et respiratoire du porc (PRRS), y compris les technologies associées aux vaccins.

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