5ht1 receptor agonists and metoclopramide for the treatment...

Details 5ht1 receptor agonists and metoclopramide for the treatment... 5ht1 receptor agonists and metoclopramide for the treatment...

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61K 31/16 (2006.01) A61K 31/166 (2006.01) A61K 31/40 (2006.01) A61K 31/4045 (2006.01) A61K 31/41 (2006.01) A61K 31/4196 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01) A61K 31/454 (2006.01) A61K 31/495 (2006.01) A61K 45/00 (2006.01) A61P 25/06 (2006.01) C07D 209/14 (2006.01) C07D 401/00 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2348543

The present invention relates to a method of treating migraine in a mammal, including a human, by administering to the mammal a 5HT1 receptor agonist, and particularly eletriptan, in combination with metoclopramide. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier, a 5HT1 receptor agonist and metoclopramide.

Procédé de traitement de la migraine chez un mammifère, dont un être humain, qui consiste à administrer à ce mammifère un agoniste de récepteur 5HT¿1?, en particulier de l'élétriptan, en combinaison avec du métoclopramide. La présente invention concerne également des compositions pharmaceutiques contenant un excipient acceptable sur le plan pharmaceutique, un agoniste de récepteur 5HT¿1? et du métoclopramide.

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