Production of pluripotent cells through inhibition of...

Details Production of pluripotent cells through inhibition of... Production of pluripotent cells through inhibition of...

C - Chemistry, Metallurgy

12

N

C12N 5/07 (2010.01)

Patent

CA 2730546

The present invention involves the identification of Bright/ ARID3 a as involved in the regulation of pluripotency in cells, and the targeting of that function for the regulation of pluripotency. Thus, methods of de-differentiating cells into pluripotent cells are provided, as well as methods for re-differentiating such cells in a controlled fashion.

L'invention concerne l'identification de la fonction Bright/ARID3 telle qu'impliquée dans la régulation de la pluripotence dans les cellules et le ciblage de cette fonction pour la régulation de la pluripotence. On obtient ainsi des procédés permettant la dédifférenciation de cellules en cellules pluripotentes, ainsi que des procédés permettant de redifférencier de telles cellules de façon contrôlée.

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