A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/275 (2006.01) A61P 1/18 (2006.01)
Patent
CA 2382529
The present invention relates to the administration of cyanohydroxybutene (CHB) to eliminate acinar cells in a subject. Subcutaneous injection of CHB at a sub-lethal dosage caused apoptosis of the substantially entire population of acinar cells. The pancreatic lesion has marked early edema with limited inflammatory infiltration, rapid synchronous onset of acinar cell apoptosis and advanced atrophy with a severely limited regenerative response. There is further provided methods of treatment of acinar cell carcinoma and pancreatitis.
La présente invention concerne une administration de cyanohydroxybutène (CHB) permettant d'éliminer les cellules acineuses d'un sujet. L'injection d'une dose sublétale de CHB provoque l'apoptose quasi générale d'une population de cellules acineuses. Une lésion pancréatique peut se manifester par un oedème précoce avec une infiltration inflammatoire limitée, un départ synchrone rapide de l'apoptose des cellules acineuses et une atrophie avancée avec une réponse régénérative limitée. L'invention concerne également des méthodes de traitement de carcinomes des cellules acineuses et de pancréatites.
Fetherstonhaugh & Co.
Kelly E. Lyndell
Pancreas Technologies Pty Ltd
LandOfFree
Treatment of pancreatic disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of pancreatic disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of pancreatic disease will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1725715