Receptor based antagonists and methods of making and using

Details Receptor based antagonists and methods of making and using Receptor based antagonists and methods of making and using

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/715 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2345109

The present invention provides a fusion polypeptide capable of binding a cytokine to form a nonfunctional complex. It also provides a nucleic acid sequence encoding the fusion polypeptide and methods of making and uses for the fusion polypeptide.

La présente invention concerne un polypeptide de fusion capable de se lier à une cytokine de façon à former un complexe non fonctionnel. L'invention concerne également, d'une part une séquence d'acides nucléiques codant ces polypeptides de fusion, et d'autre part des modes d'élaboration et d'utilisation se rapportant à ce polypeptide de fusion.

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