C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/04 (2006.01) A61K 31/4985 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2576294
The invention relates to novel substituted xanthines of general formula (I), wherein R1, R2, and X are defined as mentioned in the claims, the tautomers, enantiomers, diastereomers, mixtures, and salts thereof, which have valuable pharmaceutical properties, especially an inhibitive effect on the activity of the dipeptidyl peptidase-IV (DPP-IV) enzyme.
La présente invention concerne de nouvelles xanthines substituées de formule générale (I), dans laquelle R1, R2 et X sont tels que définis dans les revendications, ainsi que leurs tautomères, énantiomères, diastéréoisomères, mélanges et sels. Ces composés présentent des propriétés pharmacologiques intéressantes, notamment une action inhibitrice sur l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).
Eckhardt Matthias
Himmelsbach Frank
Langkopf Elke
Lotz Ralf R. H.
Tadayyon Mohammad
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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