Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/12 (2006.01) A61K 31/33 (2006.01) A61K 31/66 (2006.01) C07C 317/24 (2006.01) C07D 209/10 (2006.01) C07D 209/12 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 311/94 (2006.01) C07D 333/18 (2006.01) C07D 333/56 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 491/052 (2006.01) C07D 493/04 (2006.01) C07D 513/04 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2197895

The invention encompasses the novel compound of formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).

Nouveau composé de la formule (I) et procédé de traitement des maladies induites par la cyclooxygénase-2. Le procédé consiste à administrer au patient nécessitant un tel traitement une quantité non toxique et efficace sur le plan thérapeutique d'un composé de la formule (I). L'invention porte également sur certaines compositions pharmaceutiques destinées au traitement des maladies induites par la cyclooxygénase-2, qui renferment les composés de la formule (I).

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