Diagnostic method for brain damage-related disorders

Details Diagnostic method for brain damage-related disorders Diagnostic method for brain damage-related disorders

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2613991

A brain damage-related disorder is diagnosed in a subject by detecting at least one polypeptide, or a variant or mutant thereof, in a sample of body fluid taken from the subject, wherein the polypeptide is one for which the level is either increased 10 or decreased in cerebrospinal fluid from deceased patients compared to cerebrospinal fluid from healthy donors.

On diagnostique un trouble associé à la détérioration cérébrale chez un individu par détection d'au moins un polypeptide ou une de ses variantes ou un de ses mutants, dans un spécimen de liquide corporel prélevé chez cet individu, le niveau de ce polypeptide étant soit augmenté, soit diminué dans le liquide cérébro-spinal de patients décédés par rapport au liquide cérébro-spinal de donneurs sains.

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