Compositions of a benzenesulfonamide or...

A - Human Necessities – 61 – K

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A61K 31/18 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2525571

The present invention provides methods and compositions for the treatment of central nervous system damage in a subject. More particularly, the invention provides a combination therapy for the treatment of a central nervous system ischemic condition or a central nervous system traumatic injury comprising the administration to a subject of a cholinergic agent in combination with a benzenesulfonamide or methylsulfonylbenzene cyclooxygenase-2 selective inhibitor.

L'invention concerne des méthodes et des compositions pour le traitement d'une lésion du système nerveux central chez un patient. En particulier, l'invention concerne une polythérapie pour le traitement d'un trouble ischémique du système nerveux central ou d'une lésion traumatique du système nerveux central. Ce traitement consiste à administrer à un patient un agent cholinergique combiné à un inhibiteur sélectif de benzènesulfonamide ou de méthylsulfonylbenzène cyclooxygénase-2.

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