Dna construct for providing rna therapy

Details Dna construct for providing rna therapy Dna construct for providing rna therapy

C - Chemistry, Metallurgy

12

N

C12N 15/51 (2006.01) A61K 31/70 (2006.01) C07K 14/02 (2006.01) C07K 14/08 (2006.01) C12N 15/11 (2006.01) C12N 15/36 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2094608

2094608 9206693 PCTABS00011 A DNA construct capable of generating a relatively high copy number of therapeutic RNA molecules, including ribozymes and anti-sense RNAs, in target cells for effecting gene therapy. The construct and method of the invention are particularly useful in suppressing hapadnavirus infection and may be clinically effective in treating hepatitis B virus carriers.

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