Piperidones

Details Piperidones Piperidones

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 211/76 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 407/14 (2006.01)

Patent

CA 2273446

The present invention relates to a compound of the formula: Image or a pharmaceutically acceptable acid addition salt or solvate thereof, wherein R is C3-C7 cycloalkyl, (C3-C7 cycloalkyl)C1-C4 alkylene or benzyl; R1 is phenyl optionally substituted by 1 or 2 substituents each independently selected from fluoro and chloro; X is O or NSO2R2; and R2 is C1-C4 alkyl or halo(C1-C4)alkyl, together with processes for the preparation of, intermediates used in the preparation of, compositions containing and uses of, such compounds having tachykinin antagonist activity.

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