Use of substances inhibiting the association of smad protein...

Details Use of substances inhibiting the association of smad protein... Use of substances inhibiting the association of smad protein...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 17/02 (2006.01) A61P 27/12 (2006.01) A61P 35/00 (2006.01) C12Q 1/34 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2513593

Disclosed is a pharmaceutical composition for altering cellular responses to TGF.beta.s and/or BMPs; the composition comprising a molecule which prevents, inhibits or reduces the association of a Smad protein with a UCH, in admixture with a physiologically acceptable carrier, excipient or diluent.

L'invention concerne une composition pharmaceutique servant à modifier les réponses cellulaires aux TGF.beta. et/ou BMP; cette composition comprend une molécule qui empêche, inhibe ou réduit l'association d'une protéine Smad et d'une UCH et qui est mélangée à un véhicule, excipient ou diluant physiologiquement acceptable.

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